Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial.

@article{McElroy2008OlanzapineIT,
  title={Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial.},
  author={Susan L McElroy and Erik B Nelson and Jeffrey A. Welge and Laura A. Kaehler and Paul E. Keck},
  journal={The Journal of clinical psychiatry},
  year={2008},
  volume={69 3},
  pages={433-40}
}
OBJECTIVE Pathological gambling is associated with bipolar disorder and dopamine dysfunction. Olanzapine is a second-generation antipsychotic with mood-stabilizing properties and antagonistic activity at several dopamine receptors. The purpose of this study was to evaluate olanzapine in the treatment of pathological gambling. METHOD In this 12-week, single-center, randomized, double-blind, placebo-controlled, flexible-dose (2.5-15 mg/day) trial, 42 outpatients with pathological gambling by… CONTINUE READING

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