Olanzapine compared to quetiapine in adolescents with a first psychotic episode

  title={Olanzapine compared to quetiapine in adolescents with a first psychotic episode},
  author={PhD Celso Arango and Olalla Robles and PhD Mara Parellada and David Fraguas and Ana Ruiz-Sancho and Oscar D Medina and Arantzazu Zabala and Igor Bomb{\'i}n and PhD Dolores Moreno},
  journal={European Child & Adolescent Psychiatry},
To compare the efficacy, safety, and tolerability of olanzapine and quetiapine in adolescents with first episode psychosis. Fifty adolescents (age 16 ± 1.25) with a first episode of psychosis were randomized to quetiapine or olanzapine in a 6-month open label study. Efficacy and side effect scales, as well as vital signs and laboratory data were recorded at baseline, 7, 15, 30, 90, and 180 days (end of study). Out of the total sample included in the study, 32 patients completed the trial… CONTINUE READING


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