Okadaic acid. Protein phosphatase inhibition and muscle contractile effects.

@article{Takai1988OkadaicAP,
  title={Okadaic acid. Protein phosphatase inhibition and muscle contractile effects.},
  author={Akira Takai},
  journal={Journal of muscle research and cell motility},
  year={1988},
  volume={9 6},
  pages={563-5}
}
  • Akira Takai
  • Published 1988 in Journal of muscle research and cell motility
Okadaic acid (OA;C44H66O13) is a polyether derivative of a C38 fatty acid first isolated from marine sponges of the genus Halichondria . It is thought to be synthesized by marine diflagellates and to accumulate in the other marine organisms such as sponges and shellfishes which feed on them. Physiologically, OA has been known to have a marked contractile effect on smooth muscles and heart muscle. Recent results strongly suggest that these contractile effects are due to the inhibitory action of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…