Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight.

@article{Burris2015OffspringDM,
  title={Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight.},
  author={Heather H Burris and Andrea A. Baccarelli and Hyang-Min Byun and Alejandra J Cantoral and Allan C. Just and Ivan Pantic and Maritsa Solano-Gonz{\'a}lez and Katherine Svensson and Marcela Tamayo y Ortiz and Yan Zhao and Robert Wright and Martha M T{\'e}llez-Rojo},
  journal={Epigenetics},
  year={2015},
  volume={10 10},
  pages={913-21}
}
Prenatal smoke exposure, maternal obesity, aberrant fetal growth, and preterm birth are all risk factors for offspring metabolic syndrome. Cord blood aryl-hydrocarbon receptor repressor (AHRR) DNA methylation is responsive to maternal smoking during pregnancy. AHRR serves not only to inhibit aryl-hydrocarbon receptor (AHR) transcription, which is involved in mediating xenobiotic metabolism, but it is also involved in cell growth and differentiation. Other than maternal smoking, other predictors… CONTINUE READING
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