Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment

@article{Breen2004OffsetOP,
  title={Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment},
  author={Des Breen and Alexander Wilmer and Andrew R. Bodenham and Vagn Bach and Jan Bonde and Paul Kessler and Sven Albrecht and Soraya Shaikh},
  journal={Critical Care},
  year={2004},
  volume={8},
  pages={R21 - R30}
}
INTRODUCTION This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care. METHODS A total of 40 patients, who were aged 18 years or older and had normal/mildly impaired renal function (estimated creatinine clearance >/= 50 ml/min; n = 10) or moderate/severe renal impairment (estimated creatinine clearance <50 ml/min; n = 30), were… CONTINUE READING
25 Citations
24 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

A dosing algorithm for the use of remifentanil in providing optimal sedation and analgesia in ICU patients [abstract A405

  • A Kirkham, G Fisher, P Kessler
  • Intensive Care Med
  • 2001
2 Excerpts

A remifentanil-based technique for analgesia and sedation in ICU patients with neurotrauma: preliminary data [abstract A549

  • A Karabinis, P Hantson, +4 authors BK Upadhyaya
  • Intensive Care Med
  • 2001

The safety and efficacy of remifentanil for the provision of optimal sedation in ICU patients [abstract A407

  • A López, B Muellejans, MH Cross, C Bonome, L Morrison, A Kirkham
  • Intensive Care Med
  • 2001
1 Excerpt

Similar Papers

Loading similar papers…