Of mice and rats: key species variations in the sexual differentiation of brain and behavior.

@article{Bonthuis2010OfMA,
  title={Of mice and rats: key species variations in the sexual differentiation of brain and behavior.},
  author={Paul J. Bonthuis and Kimberly H. Cox and Brian T. Searcy and Pavan Kumar and Stuart A Tobet and Emilie F. Rissman},
  journal={Frontiers in neuroendocrinology},
  year={2010},
  volume={31 3},
  pages={341-58}
}
Mice and rats are important mammalian models in biomedical research. In contrast to other biomedical fields, work on sexual differentiation of brain and behavior has traditionally utilized comparative animal models. As mice are gaining in popularity, it is essential to acknowledge the differences between these two rodents. Here we review neural and behavioral sexual dimorphisms in rats and mice, which highlight species differences and experimental gaps in the literature, that are needed for… CONTINUE READING

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