Of mice and genes: evolution of vertebrate brain development.

  title={Of mice and genes: evolution of vertebrate brain development.},
  author={Bernd Fritzsch},
  journal={Brain, behavior and evolution},
  volume={52 4-5},
In this review the current understanding of genetic and molecular evolution of development, in particular the formation of the major axis of bilateral animals, is critically evaluated, and the early pattern formation in the hindbrain is related as much as possible to these processes. On the genetic level it is proposed that the exuberant multiplication of regulatory genes compared to that of structural genes relates to the increased flexibility of early vertebrate development. In comparisons to… CONTINUE READING

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