Of birds and mice: hematopoietic stem cell development.

@article{Godin2005OfBA,
  title={Of birds and mice: hematopoietic stem cell development.},
  author={Isabelle Godin and Ana Cumano},
  journal={The International journal of developmental biology},
  year={2005},
  volume={49 2-3},
  pages={251-7}
}
For many years it has been assumed that the ontogeny of the mammalian hematopoietic system involves sequential transfers of hematopoietic stem cells (HSCs) generated in the yolk sac blood islands, to successive hematopoietic organs as these become active in the embryo (fetal liver, thymus, spleen and eventually bone marrow). Very little was known about early events related to hematopoiesis that could take place during the 4.5 day gap separating the appearance of the yolk sac blood islands and… CONTINUE READING

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