Of Mice and Men: Aligning Mouse and Human Anatomies

  title={Of Mice and Men: Aligning Mouse and Human Anatomies},
  author={Olivier Bodenreider and Terry F. Hayamizu and Martin Ringwald and Sherri de Coronado and Songmao Zhang},
  journal={AMIA ... Annual Symposium proceedings. AMIA Symposium},
This paper reports on the alignment between mouse and human anatomies, a critical resource for comparative science as diseases in mice are used as mod-els of human disease. The two ontologies under investigation are the NCI Thesaurus (human anatomy) and the Adult Mouse Anatomical Dictionary, each comprising about 2500 anatomical concepts. This study compares two approaches to aligning ontologies. One is fully automatic, based on a combination of lexical and structural similarity; the other is… CONTINUE READING
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