Of LAP, CUPS, and DRibbles – Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation

@inproceedings{Mnz2015OfLC,
  title={Of LAP, CUPS, and DRibbles – Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation},
  author={Christian M{\"u}nz},
  booktitle={Front. Immunol.},
  year={2015}
}
Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Because MHC class II molecules are loaded with lysosomal products for CD4(+) T-cell stimulation, macroautophagy supports intracellular antigen processing onto MHC class II molecules. The molecular machinery of macroautophagy, however, does not only support this autophagic antigen processing, but seems to also modify extracellular antigen uptake for MHC class II presentation, antigen exocytosis, and packaging for… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

an evolving mechanism

  • Malhotra V. Unconventional protein secretion
  • EMBO J
  • 2013
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…