Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin.

@article{Milligan2002OestrogenicAO,
  title={Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin.},
  author={Stuart Milligan and Jatin Kalita and Victoria J Pocock and Arne Heyerick and Luc De Cooman and H Rong and Denis de Keukeleire},
  journal={Reproduction},
  year={2002},
  volume={123 2},
  pages={235-42}
}
The female flowers of the hop plant (hop cones) are used as a preservative and as a flavouring agent in beer. A novel phyto-oestrogen, 8-prenylnaringenin, was recently identified in hops and this study was undertaken to characterize the oestrogenic activity of this compound using a combination of in vitro and in vivo assays. Natural and semi-synthetic 8-prenylnaringenin showed similar bioactivities both in a yeast screen transfected with the human oestrogen receptor and in oestrogen-responsive… CONTINUE READING

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4 Excerpts

Quantitation of 8 - prenylnaringenin , a novel phytoestrogen in hops ( Humulus lupulus L . ) , hop products and beers , by benchtop HPLC using electrospray ionization

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Quantitation of 8-prenylnaringenin, a novel phytoestrogen in hops (Humulus lupulus L.), hop products and beers, by benchtop HPLC using electrospray ionization Chromatographia

  • H Rong, Y Zhao, K Lazou, D De Keukeleire, SR Milligan, P Sandra
  • 2000
6 Excerpts

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