Oestrogenic activity of parabens in MCF7 human breast cancer cells

  title={Oestrogenic activity of parabens in MCF7 human breast cancer cells},
  author={J. Byford and L. E. Shaw and M. Drew and G. Pope and P. D. Darbre},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  • J. Byford, L. E. Shaw, +2 authors P. D. Darbre
  • Published 2002
  • Chemistry, Medicine
  • The Journal of Steroid Biochemistry and Molecular Biology
  • Parabens (4-hydroxybenzoic acid esters) have been recently reported to have oestrogenic activity in yeast cells and animal models. Since the human population is exposed to parabens through their widespread use as preservatives in foods, pharmaceuticals and cosmetics, we have investigated here whether oestrogenic activity of these compounds can also be detected in oestrogen-sensitive human cells. We report on the oestrogenic effects of four parabens (methylparaben, ethylparaben, n-propylparaben… CONTINUE READING
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    Publications referenced by this paper.
    Estrogenic effects of p-hydroxybenzoic acid in CD1 mice.
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