Oestrogen receptors - an overview.

  title={Oestrogen receptors - an overview.},
  author={Eva Enmark and Jan Ake Gustafsson},
  journal={Journal of internal medicine},
  volume={246 2},
The oestrogen receptor (ER) is a ligand-activated transcription factor that mediates the effects of the steroid hormone 17beta-oestradiol in both males and females. Since the isolation and cloning of ER, the prevailing opinion has been that only one such receptor exists. The finding of a second subtype of ER (ERbeta) has caused considerable excitement and has forced endocrinologists to re-evaluate many aspects of the actions of oestrogens. In this article, we will try to summarize the current… CONTINUE READING

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