Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.

@article{Shaw2002OestrogenRA,
  title={Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.},
  author={Jacqueline Amanda Shaw and Kufre Udokang and Juan-Miguel Mosquera and Hina Chauhan and Janet Louise Jones and Rosemary A. Walker},
  journal={The Journal of pathology},
  year={2002},
  volume={198 4},
  pages={450-7}
}
The identification of a second oestrogen receptor, oestrogen receptor (ER) beta, has led to a need to assess the relative importance of the classical ERalpha and ERbeta in human breast and breast carcinomas. ERalpha and ERbeta mRNA was assessed in 61 carcinomas, 8 benign breast lesions, and 30 samples of normal breast using reverse transcriptase (RT)-nested polymerase chain reaction (PCR). Immunohistochemical analysis of ERalpha and ERbeta was performed in 62 carcinomas, the 38 non-malignant… CONTINUE READING