Oestrogen-receptor status and endocrine therapy of breast cancer: response rates and status stability.

R. E. Leake, Lucy M. Laing, Kenneth C. Calman, Fergus R Macbeth, David Crawford, D. C. Smith
Published 1981 in British Journal of Cancer

Abstract

The concentration of cellular oestrogen receptor (RE) was measured in both the soluble and nuclear-pellet fractions of biopsies from 1,000 breast cancers. Data suggest that functional steroid RE is always in equilibrium between the soluble and nuclear fractions. However, biopsies from only one-third of patients contained detectable amounts of high-affinity… (More)

DOI: 10.1038/bjc.1981.8

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References

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Showing 1-10 of 15 references

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

J C Allegra, M E Lippman, +6 authors S C Aitken
Cancer research
1979

Equilibrium: the intracellular distribution of steroid receptors.

P J Sheridan, J M Buchanan, V C Anselmo, P M Martin
Nature
1979

K. F. STOA
J. Steroid Biochem.,
1979

Occupied and unoccupied nuclear oestradiol receptor in human breast tumours: relation to oestradiol and progesterone cytosol receptors.

T Thorsen
Journal of steroid biochemistry
1979

Triple hormone-receptor assay: a more accurate predictive tool for the treatment of advanced breast cancer?

D. M. Barnes, L. G. Skinner, G. G. Ribeiro
British Journal of Cancer
1979

Uncharged nuclear receptors for estrogen in breast cancers.

W B Panko, R M MacLeod
Cancer research
1978

"False-positive" oestrogen-receptor assay in breast cancer.

B A Stoll
Lancet
1977

A. SEGALOFF
1977

Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication.

J S Meyer, B R Rao, S C Stevens, W L White
Cancer
1977

Lancet, ii, R. E. 168. LEAKE
Trends Biochem
1976

Oestrogen-receptor status and endocrine therapy of breast cancer: response rates and status stability.

Abstract

Topics

6 Figures and Tables

Cited By

Environmental Information Superhighway

Hormone receptors expression in ovarian cancer taking into account menopausal status: a retrospective study in Chinese population

Role of Receptors in Breast Cancer

Biomarkers in Breast Cancer

The biology and physiology of ‘Nolvadex’ (tamoxifen) in the treatment of breast cancer

No safe harbor.

The isolation and long-term culture of normal human endometrial epithelium and stroma. Expression of mRNAs for angiogenic polypeptides basally and on oestrogen and progesterone challenges.

Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line.

Investigation of the origin of variant, truncated estrogen receptor-like mRNAs identified in some human breast cancer biopsy samples

cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo.

References

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

Equilibrium: the intracellular distribution of steroid receptors.

Nuclear uptake of oestradiol- 17fl in human mammary tumour tissue

Occupied and unoccupied nuclear oestradiol receptor in human breast tumours: relation to oestradiol and progesterone cytosol receptors.

Triple hormone-receptor assay: a more accurate predictive tool for the treatment of advanced breast cancer?

Uncharged nuclear receptors for estrogen in breast cancers.

"False-positive" oestrogen-receptor assay in breast cancer.

Current status of estrogen and progesterone receptors in breast cancer

Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication.

Current views on oestrogen receptors

Slides referencing similar topics

Oestrogen-receptor status and endocrine therapy of breast cancer: response rates and status stability.

Abstract

Topics

6 Figures and Tables

Cited By

Environmental Information Superhighway

Hormone receptors expression in ovarian cancer taking into account menopausal status: a retrospective study in Chinese population

Role of Receptors in Breast Cancer

Biomarkers in Breast Cancer

The biology and physiology of ‘Nolvadex’ (tamoxifen) in the treatment of breast cancer

No safe harbor.

The isolation and long-term culture of normal human endometrial epithelium and stroma. Expression of mRNAs for angiogenic polypeptides basally and on oestrogen and progesterone challenges.

Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line.

Investigation of the origin of variant, truncated estrogen receptor-like mRNAs identified in some human breast cancer biopsy samples

cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo.

References

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

Equilibrium: the intracellular distribution of steroid receptors.

Nuclear uptake of oestradiol- 17fl in human mammary tumour tissue

Occupied and unoccupied nuclear oestradiol receptor in human breast tumours: relation to oestradiol and progesterone cytosol receptors.

Triple hormone-receptor assay: a more accurate predictive tool for the treatment of advanced breast cancer?

Uncharged nuclear receptors for estrogen in breast cancers.

"False-positive" oestrogen-receptor assay in breast cancer.

Current status of estrogen and progesterone receptors in breast cancer

Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication.

Current views on oestrogen receptors

Similar Papers

Slides referencing similar topics