Oestrogen and benign prostatic hyperplasia: effects on stromal cell proliferation and local formation from androgen.

Abstract

Oestrogens have been implicated as a cause of benign prostatic hyperplasia (BPH). Previous animal studies led to the hypothesis that oestrogens can stimulate prostate growth, resulting in hyperplasia of the gland. In humans, the precise role of oestrogens in BPH pathogenesis is currently unclear. We investigated the direct effects of oestradiol on the… (More)
DOI: 10.1677/JOE-07-0470

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