Oestradiol inhibits the release of tumour necrosis factor but not interleukin 6 from adult human osteoblasts in vitro

@article{Rickard1992OestradiolIT,
  title={Oestradiol inhibits the release of tumour necrosis factor but not interleukin 6 from adult human osteoblasts in vitro},
  author={David L Rickard and Graham Russell and Maxine Gowen},
  journal={Osteoporosis International},
  year={1992},
  volume={2},
  pages={94-102}
}
Oestrogens may control bone remodelling by directly regulating the synthesis of cytokines in osteoblasts. We have investigated the effects of oestradiol on the release of two cytokines, IL-6 and TNF, known to be produced by normal human osteoblast-like cells. The effect of oestradiol on basal and stimulated IL-6 and TNF release was investigated. The… CONTINUE READING