Oestradiol, sexual receptivity and cytosol progestin receptors in rat hypothalamus

@article{Parsons1981OestradiolSR,
  title={Oestradiol, sexual receptivity and cytosol progestin receptors in rat hypothalamus},
  author={Bruce V. Parsons and Thomas C. Rainbow and Donald W. Pfaff and Bruce S. McEwen},
  journal={Nature},
  year={1981},
  volume={292},
  pages={58-59}
}
Oestradiol and progesterone regulate feminine reproductive behaviour in rodents. Their administration induces changes of biosynthetic activity in the hypothalamus1, one of which—the induction of progestin receptors—is correlated with the induction of sexual receptivity2–4, conveniently indicated (in the rat) by the lordosis reflex of the mounted female. We have attempted to define what might be considered as a minimal regime of oestradiol administration—one which is just ‘sufficient’ for… CONTINUE READING
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