Oenology: Red wine procyanidins and vascular health

@article{Corder2006OenologyRW,
  title={Oenology: Red wine procyanidins and vascular health},
  author={Roger Corder and William Mullen and Noorafza Q. Khan and Serena C. Marks and Elizabeth G. Wood and Martin J. Carrier and Alan Crozier},
  journal={Nature},
  year={2006},
  volume={444},
  pages={566-566}
}
Regular, moderate consumption of red wine is linked to a reduced risk of coronary heart disease and to lower overall mortality, but the relative contribution of wine's alcohol and polyphenol components to these effects is unclear. Here we identify procyanidins as the principal vasoactive polyphenols in red wine and show that they are present at higher concentrations in wines from areas of southwestern France and Sardinia, where traditional production methods ensure that these compounds are… 
Review Wine and health: state of proofs and research needs
TLDR
Wine polyphenol mechanisms of action will be reviewed in connection with the mechanism the development of atherosclerotic cardiovascular disease (ASCVD) and selected clinical studies published in 2004-2008 were reviewed.
Wine and health: state of proofs and research needs
TLDR
In this review, wine polyphenol mechanisms of action will be reviewed in connection with the mechanism the development of atherosclerotic cardiovascular disease (ASCVD).
Influence of grape variety and their phenolic composition on vasorelaxing activity of young red wines
Red wine has been reported to exert beneficial effects in preventing cardiovascular diseases probably due to their polyphenols constituents. The vasorelaxant capacity and phenolic composition of four
Alcohol and wine in relation to cancer and other diseases
TLDR
The pros and cons of moderate alcohol and wine consumption are focused on and the development of future potential nutraceutical strategies are advocated.
Research on the content of trans-resveratrol in Romanian wines
Scientific activity in the field of oenology became more intense over time, being necessary regarding the quality of grapes and hence of wine. Recent proofs show that red wine has health benefits,
Contribution of Red Wine Consumption to Human Health Protection
TLDR
The main aim of this review is to summarize the current findings about the positive influence of wine consumption on human organ function, chronic diseases, and the reduction of damage to the cardiovascular system.
...
...

References

SHOWING 1-10 OF 16 REFERENCES
Phenolics from commercialized grape extracts prevent early atherosclerotic lesions in hamsters by mechanisms other than antioxidant effect.
TLDR
Results suggests that phenolic extracts from grape seeds and marc are beneficial in inhibiting atherosclerosis by indirect mechanism(s).
Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health
TLDR
The antioxidant effects of flavonoid‐rich foods may reduce cardiovascular disease risk and may underlie the protective effects of tea consumption with cardiovascular disease.
Wine, beer, and mortality in middle-aged men from eastern France.
TLDR
In eastern France, moderately drinking only wine was associated with a lower all-cause mortality, although drinking both wine and beer reduced the risk of cardiovascular death.
Apple procyanidin oligomers absorption in rats after oral administration: analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry.
TLDR
The results suggest that ACTs are absorbed and directly involved in physiological functions in the rats and the limits of the absorption of apple procyanidins in the polymerization degree are investigated.
CIRCULATION
Health: Endothelin-1 synthesis reduced by red wine
TLDR
It is shown that red wines strongly inhibit the synthesis of endothelin-1, a vasoactive peptide that is crucial in the development of coronary atherosclerosis.
Meta-Analysis of Wine and Beer Consumption in Relation to Vascular Risk
TLDR
Evidence of a significant inverse association between light-to-moderate wine consumption and vascular risk is shown and a similar, although smaller association was also apparent in beer consumption studies.
J. Agric. Food. Chem
  • J. Agric. Food. Chem
  • 2006
...
...