Oedema fluid formation within contused brain tissue as a cause of medically uncontrollable elevation of intracranial pressure: the role of surgical therapy.

@article{Katayama1990OedemaFF,
  title={Oedema fluid formation within contused brain tissue as a cause of medically uncontrollable elevation of intracranial pressure: the role of surgical therapy.},
  author={Yoichi Katayama and Takashi Tsubokawa and Shukichi Miyazaki and Tatsuro Kawamata and Atsuo Yoshino},
  journal={Acta neurochirurgica. Supplementum},
  year={1990},
  volume={51},
  pages={308-10}
}
In patients with focal cerebral contusions, medical therapies have generally been advocated unless haemorrhages significantly contributing to the elevated intracranial pressure (ICP) exist. We report here several lines of clinical evidence which indicate that (1) enormous amount of extracellular oedema fluid is formed within contused brain tissue, (2) the formation of extracellular oedema fluid within contused brain tissue alone can be a cause of medically uncontrollable elevation of ICP and (3… CONTINUE READING

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