Odor-Induced Variation in Anxiety-Like Behavior in Mice is Associated with Discrete and Differential Effects on Mesocorticolimbic Cholecystokinin mRNA Expression

@article{Hebb2002OdorInducedVI,
  title={Odor-Induced Variation in Anxiety-Like Behavior in Mice is Associated with Discrete and Differential Effects on Mesocorticolimbic Cholecystokinin mRNA Expression},
  author={Andrea L.O. Hebb and Robert M. Zacharko and H{\'e}l{\`e}ne Dominguez and France Trudel and Sylvie Laforest and Guy Drolet},
  journal={Neuropsychopharmacology},
  year={2002},
  volume={27},
  pages={744-755}
}
  • Andrea L.O. Hebb, Robert M. Zacharko, +3 authors Guy Drolet
  • Published in Neuropsychopharmacology 2002
  • Psychology, Medicine
  • The present investigation assessed alterations in mesocorticolimbic cholecystokinin (CCK) mRNA following novel predator and non-predator odor exposure and light-dark testing in CD-1 mice. In brief, acute exposure of CD-1 mice to the predator odor, 2,5-dihydro-2, 4,5-trimethylthiazoline (TMT; the major component of the anal gland secretions of the red fox), or the control odor, butyric acid (BA), suppressed rearing behavior during odor presentation, subsequently induced anxiety in the light dark… CONTINUE READING

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