Odontogenic potential of bone marrow mesenchymal stem cells.

  title={Odontogenic potential of bone marrow mesenchymal stem cells.},
  author={Zhiyong Li and Ling Chen and Lei Liu and Yunfeng Lin and Sheng-Wei Li and Weidong Tian},
  journal={Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons},
  volume={65 3},
PURPOSE This study aimed to investigate the odontogenic potential of bone marrow mesenchymal stem cells (BM-MSCs) for seeding in tooth regeneration. MATERIALS AND METHODS In this study, BM-MSCs were co-cultured with oral epithelial cells derived from rat embryos. Expression of the odontogenic genes Pax9, DMP1, and DSPP was detected by the reverse-transcription polymerase chain reaction (RT-PCR) technique. To further characterize the odontogenic potential of BM-MSCs, the gold standard in vivo… CONTINUE READING