Odontoblast TRP channels and thermo/mechanical transmission.

  title={Odontoblast TRP channels and thermo/mechanical transmission.},
  author={Aran Son and Y M Yang and Ji Hee Hong and S I Lee and Yoshiyuki Shibukawa and Dong Min Shin},
  journal={Journal of dental research},
  volume={88 11},
Odontoblasts function as mechanosensory receptors because of the expression of mechanosensitive channels in these cells. However, it is unclear if odontoblasts direct the signal transmission evoked by heat/cold or osmotic changes. This study investigated the effects of heat/cold or osmotic changes on calcium signaling and the functional expression of the thermo/mechanosensitive transient receptor potential (TRP) channels in primary cultured mouse odontoblastic cells, with the use of RT-PCR… CONTINUE READING