Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study

@inproceedings{Nguyen2013OcularTA,
  title={Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study},
  author={Quan D. Nguyen and Mohamed Ibrahim and Anthony Watters and Millena G. Bittencourt and Jithin Yohannan and Yasir Jamal Sepah and James P. Dunn and Joel Naor and Naveed Shams and Ovais Shaikh and Henry Alexander Leder and Diana V. Do},
  booktitle={Journal of ophthalmic inflammation and infection},
  year={2013}
}
BACKGROUND The purpose of this study is to evaluate the ocular tolerability and efficacy of sirolimus administered as subconjunctival or intravitreal injections in patients with non-infectious uveitis. Sirolimus as a Therapeutic Approach for Uveitis (SAVE) is a prospective, randomized, open-label, interventional study. Thirty patients were enrolled and randomized in 1:1 ratio to receive either intravitreal injections of 352 μg sirolimus or subconjunctival injections of 1,320 μg at days 0, 60… CONTINUE READING

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Intravitreal administration of ocular formulation of sirolimus in rabbits and humans

  • S Mudumba, H Takanaga, P Bezwada, L Wilson, J Naor
  • Invest Ophthalmol Vis Sci
  • 2012
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