Ocular tissue absorption of clindamycin phosphate.

Abstract

Clindamycin phosphate, a new semisynthetic antibiotic that is effective in the treatment of toxoplasmosis and of infections caused by Gram-positive bacteria, was found to be highly concentrated in the choroid, iris, and retina of the pigmented rabbit eye after a single intramuscular injection of 75 mg/kg. Drug levels considered adequate for the control of… (More)

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