Ocular pharmacokinetic study of a corticosteroid by 19F MR.

Abstract

Traditional ocular pharmacokinetic studies are invasive and cannot be easily applied to humans in vivo. To acquire in vivo ocular pharmacokinetic data noninvasively, (19)F MR on a 3T clinical scanner was used to follow the real time dynamics of a corticosteroid in the eye. (1)H MR was also performed to locate the site of administration. Triamcinolone… (More)
DOI: 10.1016/j.exer.2010.05.022

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