Ocular pharmacokinetic study of a corticosteroid by 19F MR.


Traditional ocular pharmacokinetic studies are invasive and cannot be easily applied to humans in vivo. To acquire in vivo ocular pharmacokinetic data noninvasively, (19)F MR on a 3T clinical scanner was used to follow the real time dynamics of a corticosteroid in the eye. (1)H MR was also performed to locate the site of administration. Triamcinolone… (More)
DOI: 10.1016/j.exer.2010.05.022

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