Ocular inserts for controlled delivery of pefloxacin mesylate: preparation and evaluation.

@article{Sultana2005OcularIF,
  title={Ocular inserts for controlled delivery of pefloxacin mesylate: preparation and evaluation.},
  author={Yasmin Sultana and Mohammad Aqil and Asgar Ali},
  journal={Acta pharmaceutica},
  year={2005},
  volume={55 3},
  pages={305-14}
}
Pefloxacin mesylate is a flouroquinolone antibacterial drug effective in the treatment of bacterial conjunctivitis. The objective of the present work was to develop ocular inserts of pefloxacin mesylate and evaluate their potential for sustained ocular delivery. Reservoir-type ocular inserts were prepared by the film casting technique in teflon coated Petri dishes and characterized in vitro by drug release studies using a flow-through apparatus that simulated the eye conditions. Six… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 16 references

Modelling of drug release from polymer matrices: Effect of drug

  • S. K. El-Arini, H. Leuenberger
  • loading, Int. J. Pharm
  • 1995

Ocular sustained delivery of prednisolone using hyaluronic acid benzyl ester

  • L. R. Hume, H. K. Lee, L. Benedetti, Y. D. Sanzgiri, E. M. Topp, V. J. Stella
  • films, Int. J. Pharm
  • 1994

Ocular sustained delivery of prednisolone using hyaluronic acid benzyl ester films

  • J. Cobby Grass, M. C. Makoid
  • Int . J . Pharm .
  • 1994

Precorneal, Corneal and Postcorneal Factors, in Drugs and Pharmaceutical Sciences (Ed

  • V.H.L. Lee
  • J. Swarbrick), Vol 58, Marcel Dekker Inc., New…
  • 1993
1 Excerpt

Cromolyn sodium in the treatment of allergic conjunctivitis caused by congress

  • A. Ali, S. N. Sharma
  • grass, Ind. J. Hosp. Pharm
  • 1991
1 Excerpt

In-vivo performance of 3H dexamethasone ophthalmic film delivery systems in the rabbit

  • M. A. Attia, M. A. Kassem, S. Safwat
  • eye, Int. J. Pharm
  • 1988

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