Ocular immune reactants in patients dying with systemic lupus erythematosus.

  title={Ocular immune reactants in patients dying with systemic lupus erythematosus.},
  author={A G Karpik and M. Michele Schwartz and L E Dickey and Barbara W. Streeten and Jaclyn Landau Roberts},
  journal={Clinical immunology and immunopathology},
  volume={35 3},
Immunopathologic studies were performed on ocular tissue obtained at autopsy in five patients with systemic lupus erythematosus (SLE). The immunopathologic findings were correlated with histopathologic and clinical features of SLE. Immune reactants were demonstrated by direct immunofluorescence in all patients in a granular pattern suggesting immune complex aggregates; control ocular tissues from four patients without SLE were negative. Ultrastructural studies demonstrated corresponding… CONTINUE READING


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