Ocular hypotensive effect of PhXA41 in patients with ocular hypertension or primary open-angle glaucoma.

@article{Hotehama1993OcularHE,
  title={Ocular hypotensive effect of PhXA41 in patients with ocular hypertension or primary open-angle glaucoma.},
  author={Y Hotehama and Hiromu K. Mishima and Yoshiaki Kitazawa and Kanjiro Masuda},
  journal={Japanese journal of ophthalmology},
  year={1993},
  volume={37 3},
  pages={270-4}
}
A study was carried out to assess the clinical efficacy of PhXA41, a new phenyl-substituted prostaglandin F2 alpha-isopropyl ester analogue, using a single administration in 35 subjects with ocular hypertension or primary open-angle glaucoma. PhXA41 caused a dose-dependent intraocular pressure (IOP) reduction which continued 24 hours or more after administration. The mean IOP reduction 8 hours after treatment compared with the baseline IOP was 3.4, 4.9 and 5.9 mmHg for the doses of 25, 50 and… CONTINUE READING

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