Ocular bioanalysis: challenges and advancements in recent years for these rare matrices.

@article{Heinig2017OcularBC,
  title={Ocular bioanalysis: challenges and advancements in recent years for these rare matrices.},
  author={Katja Heinig and Enric Bertran and Julian J. Potter and Daniela Fraier},
  journal={Bioanalysis},
  year={2017},
  volume={9 24},
  pages={
          1997-2014
        }
}
There are many ocular diseases still presenting unmet medical needs. Therefore, new ophthalmologic drugs are being developed. Bioanalysis of eye compartments (along with plasma and other tissues) is important to determine exposure of the target organ to the drug and to help interpret local pharmacological or toxic effects. This review article identifies several challenges that occur within ocular bioanalysis. They include sample collection and preparation, analytical issues, sourcing control… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.