Ocular angiogenesis: mechanisms and recent advances in therapy.

  title={Ocular angiogenesis: mechanisms and recent advances in therapy.},
  author={Medha Rajappa and Parul Saxena and Jasbir Kaur},
  journal={Advances in clinical chemistry},
Ocular angiogenesis, the formation of new blood vessels from the existing vascular tree, is an important cause for severe loss of vision. It can occur in a spectrum of ocular disorders such as age-related macular degeneration (AMD), diabetic retinopathy, retinal artery or vein occlusion, and retinopathy of prematurity (ROP). One of the underlying causes of vision loss in proliferative retinal diseases is the increased vascular permeability leading to retinal edema, vascular fragility resulting… CONTINUE READING