Ocular Motor Nerve Development in the Presence and Absence of Extraocular Muscle

@article{Michalak2017OcularMN,
  title={Ocular Motor Nerve Development in the Presence and Absence of Extraocular Muscle},
  author={Suzanne M. Michalak and Mary C Whitman and Jong G Park and Max A Tischfield and Elaine H. Nguyen and Elizabeth C. Engle},
  journal={Investigative Ophthalmology \& Visual Science},
  year={2017},
  volume={58},
  pages={2388 - 2396}
}
Purpose To spatially and temporally define ocular motor nerve development in the presence and absence of extraocular muscles (EOMs). Methods Myf5cre mice, which in the homozygous state lack EOMs, were crossed to an IslMN:GFP reporter line to fluorescently label motor neuron cell bodies and axons. Embryonic day (E) 11.5 to E15.5 wild-type and Myf5cre/cre:IslMN:GFP whole mount embryos and dissected orbits were imaged by confocal microscopy to visualize the developing oculomotor, trochlear, and… 

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