Octreotide in relieving gastrointestinal symptoms due to bowel obstruction.

  title={Octreotide in relieving gastrointestinal symptoms due to bowel obstruction.},
  author={Sebastiano L Mercadante and Elena Spoldi and Augusto T Caraceni and Salvatore Maddaloni and M. Tullia Simonetti},
  journal={Palliative medicine},
  volume={7 4},
Gastrointestinal obstruction is a common problem in advanced malignant disease, but its management remains controversial. In those patients for whom surgery is not appropriate, medical intervention is the only remaining option. We present a series of 14 patients with intestinal obstruction who were managed with subcutaneous injections of octreotide, a somatostatin analogue which reduces the volume of gastrointestinal secretions. Good control of vomiting was achieved in 12 patients, and no major… CONTINUE READING


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