Octamer independent activation of transcription from the kappa immunoglobulin germline promoter.

  title={Octamer independent activation of transcription from the kappa immunoglobulin germline promoter.},
  author={Anila Prabhu and Darin P O'Brien and G L Weisner and Robert B Fulton and Brian G. Van Ness},
  journal={Nucleic acids research},
  volume={24 23},
Previous analyses of immunoglobulin V region promoters has led to the discovery of a common octamer motif which is functionally important in the tissue-specific and developmentally regulated transcriptional activation of immunoglobulin genes. The germline promoters (Ko) located upstream of the J region gene segments of the kappa locus also contain an octamer motif (containing a single base pair mutation and referred to as the variant octamer) which has been shown previously to bind Oct-1 and… CONTINUE READING
5 Citations
18 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 18 references


  • H S Radomska, C-P Shen, T Kadesch, L A Eckhardt
  • Immunity
  • 1994


  • R Fulton, Van Ness
  • Biotechniques
  • 1993

Genes Dev

  • L M Corcoran, M Karvelas, G J Nossal, Z S Ye, T Jacks, D Baltimore
  • Genes Dev
  • 1993

J. Biol. Chem

  • C Thevenin, B P Lucas, E J Kozlow, J H Kehrl
  • J. Biol. Chem
  • 1993

Eur. J. Immunol

  • A Thompson, E Timmers, M J Kenter, M E Kraakman, R W Hendriks, R K Schuurman
  • Eur. J. Immunol
  • 1992

Annu. Rev. Immunol

  • L M Staudt, M J Lenardo
  • Annu. Rev. Immunol
  • 1991

Mol. Cell. Biol. Cell

  • J M Pongubala, M L Atchison, +9 authors H Sakano
  • Mol. Cell. Biol. Cell
  • 1991

EMBO J. Mol. Cell. Biol

  • M L Atchison, V Delmas, R P Perry
  • EMBO J. Mol. Cell. Biol
  • 1990


  • Schwartz, O Virelizier, J L Montagnier, L Hazan
  • Gene
  • 1990

Nucleic Acids Res

  • K B Meyer, M J Sharpe, M A Surani, M S Neuberger
  • Nucleic Acids Res
  • 1990

Similar Papers

Loading similar papers…