Octamer independent activation of transcription from the kappa immunoglobulin germline promoter.

@article{Prabhu1996OctamerIA,
  title={Octamer independent activation of transcription from the kappa immunoglobulin germline promoter.},
  author={Anila Prabhu and Darin P O'Brien and G L Weisner and Robert B Fulton and Brian G. Van Ness},
  journal={Nucleic acids research},
  year={1996},
  volume={24 23},
  pages={4805-11}
}
Previous analyses of immunoglobulin V region promoters has led to the discovery of a common octamer motif which is functionally important in the tissue-specific and developmentally regulated transcriptional activation of immunoglobulin genes. The germline promoters (Ko) located upstream of the J region gene segments of the kappa locus also contain an octamer motif (containing a single base pair mutation and referred to as the variant octamer) which has been shown previously to bind Oct-1 and… CONTINUE READING
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