Oct-4 mRNA and protein expression during human preimplantation development.

@article{Cauffman2005Oct4MA,
  title={Oct-4 mRNA and protein expression during human preimplantation development.},
  author={Greet Cauffman and Hilde van de Velde and Inge Liebaers and Andr{\'e} C. van Steirteghem},
  journal={Molecular human reproduction},
  year={2005},
  volume={11 3},
  pages={
          173-81
        }
}
The transcription factor OCT-4 is regarded as a critical factor in controlling mammalian early embryonic development because of its role in toti-/pluripotency. In human preimplantation embryos, OCT-4 studies are limited to RNA analysis of abnormally developing embryos. This study thoroughly investigated the expression pattern of OCT-4 throughout the human preimplantation development. Expression was examined by single-cell RT-PCR or indirect immunocytochemistry in 36 single oocytes of various… CONTINUE READING
Highly Cited
This paper has 111 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 61 extracted citations

Trophectoderm lineage determination in cattle.

Developmental cell • 2011
View 5 Excerpts
Highly Influenced

Transcription Factors That Regulate Trophoblast Development and Function.

Progress in molecular biology and translational science • 2017
View 1 Excerpt

111 Citations

051015'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 111 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 52 references

PGD in 47,XXY Klinefelter's syndrome patients.

Human reproduction update • 2003
View 4 Excerpts
Highly Influenced