Oct-1, to go or not to go? That is the PolII question.

  title={Oct-1, to go or not to go? That is the PolII question.},
  author={Alena Pance},
  journal={Biochimica et biophysica acta},
  volume={1859 6},
The Oct transcription factors recognise an octamer DNA element from which they regulate transcription of specific target genes. Oct-1 is the only member of the subfamily that is ubiquitously expressed and has a wide role in transcriptional control. Through interaction with various partner proteins, Oct-1 can modulate accessibility to the chromatin to recruit the transcription machinery and form the pre-initiation complex. The recruited PolII is induced to initiate transcription and stalled… CONTINUE READING
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