• Corpus ID: 21691104

Ocimum sanctum L. a potential angiotensin converting enzyme (ACE) inhibitor useful in hypertension

@article{Chaudhary2014OcimumSL,
  title={Ocimum sanctum L. a potential angiotensin converting enzyme (ACE) inhibitor useful in hypertension},
  author={Sushil Kumar Chaudhary and Pulok Kumar Mukherjee and Niladri Maity and Neelesh Kumar Nema and Santanu Bhadra and Bishnu Pada Saha},
  journal={Indian Journal of Natural Products and Resources},
  year={2014},
  volume={5},
  pages={83-87}
}
The main objective of this study was to determine the in vitro Angiotensin Converting Enzyme (ACE) inhibition and antioxidant activity of standardized extract of the Ocimum sanctum L. leaves and its fractions. The ACE inhibition activity and antioxidant activity were investigated by UV method. In ACE inhibition method, the synthetic substrate hippuryl-L-histidyl-L-leucine was allowed to react with a test sample containing ACE, to produce hippuric acid. Dried hippuric acid was dissolved in… 

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