Ochratoxin A Producing Fungi, Biosynthetic Pathway and Regulatory Mechanisms

@inproceedings{Wang2016OchratoxinAP,
  title={Ochratoxin A Producing Fungi, Biosynthetic Pathway and Regulatory Mechanisms},
  author={Yanli Wang and Liuqing Wang and Fei Liu and Qi Wang and Jonathan Nimal Selvaraj and Fuguo Xing and Yueju Zhao and Yang Liu},
  booktitle={Toxins},
  year={2016}
}
Ochratoxin A (OTA), mainly produced by Aspergillus and Penicillum species, is one of the most important mycotoxin contaminants in agricultural products. It is detrimental to human health because of its nephrotoxicity, hepatotoxicity, carcinogenicity, teratogenicity, and immunosuppression. OTA structurally consists of adihydrocoumarin moiety linked with l-phenylalanine via an amide bond. OTA biosynthesis has been putatively hypothesized, although several contradictions exist on some processes of… CONTINUE READING