Occurrence of three cases of carcinoma in individuals with Crohn's disease treated with metronidazole.

@article{Krause1985OccurrenceOT,
  title={Occurrence of three cases of carcinoma in individuals with Crohn's disease treated with metronidazole.},
  author={John Richard Krause and H Q Ayuyang and L D Ellis},
  journal={The American journal of gastroenterology},
  year={1985},
  volume={80 12},
  pages={978-82}
}
Controversy exists regarding the safety of metronidazole. Experimental studies have suggested both a carcinogenic and mutagenic effect in animals. In women treated with metronidazole for trichomoniasis which involves low dosages and short time periods, no carcinogenic effect was noted. Metronidazole is also used in the treatment of Crohn's disease which… CONTINUE READING