Occurrence of saxitoxin and other toxins in the liver of the pufferfish Takifugu pardalis.

@article{Kodama1983OccurrenceOS,
  title={Occurrence of saxitoxin and other toxins in the liver of the pufferfish Takifugu pardalis.},
  author={Michiko Kodama and Takehiko Ogata and Tamao Noguchi and Junko Maruyama and Kenji Hashimoto},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={1983},
  volume={21 6},
  pages={897-900}
}
Highly toxic livers of the pufferfish Takifugu pardalis were extracted with acidic ethanol. The toxins extracted were partially purified by chromatography on Bio-Gel P-2 and then Bio-Rex 70, resulting in separation into three fractions I, II and III. ratios of total mouse units per fraction were approximately 0.1:100:0.01, respectively, with tetrodotoxin (TTX) as standard. By TLC, electrophoresis and a TTX analyzer, Fr. II was identified as TTX and, unexpectedly, Fr. III as saxitoxin, while Fr… CONTINUE READING