Occurrence of overlooked zoonotic tuberculosis: detection of Mycobacterium bovis in human cerebrospinal fluid.

@article{Shah2006OccurrenceOO,
  title={Occurrence of overlooked zoonotic tuberculosis: detection of Mycobacterium bovis in human cerebrospinal fluid.},
  author={Nipam P Shah and Amit Singhal and A. K. Jain and P. Surendra Kumar and Singh S Uppal and M V P Srivatsava and Hanumanthappa Krishna Prasad},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 4},
  pages={1352-8}
}
The paucibacillary nature of the cerebrospinal fluid (CSF) has been a major obstacle in the diagnosis of human tuberculous meningitis (TBM). This study shows that with molecular techniques direct precise determination to the species level of mycobacterial pathogens can be made. The present report describes the utility of a nested PCR (N-PCR) assay (A. Mishra, A. Singhal, D. S. Chauhan, V. M. Katoch, K. Srivastava, S. S. Thakral, S. S. Bharadwaj, V. Sreenivas, and H. K. Prasad, J. Clin… CONTINUE READING
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