Occurrence of inhibitors in previously untreated or minimally treated patients with haemophilia A after exposure to a plasma-derived solvent-detergent factor VIII concentrate.

@article{Gringeri2006OccurrenceOI,
  title={Occurrence of inhibitors in previously untreated or minimally treated patients with haemophilia A after exposure to a plasma-derived solvent-detergent factor VIII concentrate.},
  author={Alessandro Gringeri and Mara Silvia Monzini and G Tagariello and Francesco A Scaraggi and Pier M Mannucci},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2006},
  volume={12 2},
  pages={128-32}
}
A solvent-detergent virus-inactivated plasma-derived FVIII concentrate (SD-pdFVIII) has been employed for treatment of Italian patients with haemophilia A for 15 years. This product is a non-monoclonally purified, high purity FVIII concentrate, containing large amounts of von Willebrand factor (VWF). A retrospective survey was carried out in Italy in order… CONTINUE READING