Occurrence of diverse mutations in isoniazid- and rifampicin-resistant Mycobacterium tuberculosis isolates from autochthonous and immigrant populations of Saudi Arabia.

@article{Varghese2014OccurrenceOD,
  title={Occurrence of diverse mutations in isoniazid- and rifampicin-resistant Mycobacterium tuberculosis isolates from autochthonous and immigrant populations of Saudi Arabia.},
  author={Bright Varghese and Mohamed M. Shoukri and Ziad Memish and Naila Abuljadayel and Raafat F. Alhakeem and Fahad A. Alrabiah and Sahal Al-Hajoj},
  journal={Microbial drug resistance},
  year={2014},
  volume={20 6},
  pages={623-31}
}
For the first time in Saudi Arabia, the impact of a patient's ethnic background on mutations conferring resistance to rifampicin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis isolates was analyzed on a nationwide sample collection. Four hundred fifteen isolates were subjected to drug susceptibility testing, mutation analysis, spoligotyping, and 24… CONTINUE READING