Occurrence of changes in human rotavirus serotypes with concurrent changes in genomic RNA electropherotypes.

@article{Nakagomi1988OccurrenceOC,
  title={Occurrence of changes in human rotavirus serotypes with concurrent changes in genomic RNA electropherotypes.},
  author={Toyoko Nakagomi and Kaoru Akatani and Nobuko Ikegami and Noriko Katsushima and Osamu Nakagomi},
  journal={Journal of clinical microbiology},
  year={1988},
  volume={26 12},
  pages={2586-92}
}
To investigate the serotypic and genetic diversity of human rotavirus strains, we have tested 513 and 519 fecal rotavirus specimens, respectively, by an enzyme-linked immunosorbent assay with serotype-specific monoclonal antibodies and by polyacrylamide gel electrophoresis of the segmented RNA genome. Of the 513 specimens, 375 were typed as serotype 1 (47.3%), serotype 2 (2.9%), serotype 3 (2.9%), or serotype 4 (17.7%). In addition, a presumptive new human serotype, tentatively referred to as… CONTINUE READING