Occurrence of BCR-ABL rearrangement in a Philadelphia chromosome-negative patient with 5q and 13q deletions and myeloproliferative syndrome.

Abstract

We report the case of a patient with a myeloproliferative syndrome and traits of myelodysplasia and myelofibrosis whose karyotype showed 5q and 13q deletions, as well as Philadelphia chromosome negativity. A molecular biology study performed by Southern blot, with a probe covering the M-bcr region, led to detection of three bands other than the germinal… (More)

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@article{Villegas1998OccurrenceOB, title={Occurrence of BCR-ABL rearrangement in a Philadelphia chromosome-negative patient with 5q and 13q deletions and myeloproliferative syndrome.}, author={A. Villegas and Estefan{\'i}a Anguita and Favio A Gonz{\'a}lez and Maria In{\^e}s Tiraboschi Ferro and Carlos M San Rom{\'a}n}, journal={Cancer genetics and cytogenetics}, year={1998}, volume={100 1}, pages={1-4} }