• DOI:10.1093/JAOAC/84.3.666
• Corpus ID: 26634772

Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products.

@article{Black2001OccurrenceO1,
  title={Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products.},
  author={Rebecca E. Black and Forrest James Hurley and Donald C Havery},
  journal={Journal of AOAC International},
  year={2001},
  volume={84 3},
  pages={
          666-70
        }
}

• R. Black, F. J. Hurley, D. Havery
• Published 1 May 2001
• Chemistry
• Journal of AOAC International

Surveys of cosmetic raw materials and finished products for the presence of the carcinogen 1,4-dioxane have been conducted by the U.S. Food and Drug Administration since 1979. Analytical methods are described for the determination of 1,4-dioxane in ethoxylated cosmetic raw materials and cosmetic finished products. 1,4-Dioxane was isolated by azeotropic atmospheric distillation and determined by gas chromatography using n-butanol as an internal standard. A solid-phase extraction procedure based on a previously published method for the determination of 1,4-dioxane in cosmetic finished products was also used. 1,4-Dioxane was found in ethoxylated raw materials at levels up to 1410 ppm, and at levels up to 279 ppm in cosmetic finished products. Levels of 1,4-dioxane in excess of 85 ppm in children's shampoos indicate that continued monitoring of raw materials and finished products is warranted.