Occurrence and significance of Clostridium difficile in faecal specimens of hospitalized children.

@article{Karsch1989OccurrenceAS,
  title={Occurrence and significance of Clostridium difficile in faecal specimens of hospitalized children.},
  author={W Karsch and E Strelau and W D Grahlow and Elizabeth W. Fischer and Reinhard Schulz},
  journal={Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology},
  year={1989},
  volume={270 3},
  pages={441-8}
}
Stool specimens from 766 hospitalized children, 418 with diarrhoea and 348 controls, were investigated for C. difficile. In both groups the rate of isolation was highest (about 30%) during the first year of life, dropping to nearly 5% in older children. There was no significant difference in the frequency of C. difficile in children with diarrhoea and the controls nor was there a significant influence of previous antibiotic therapy on the rate of isolation. 111/135 strains (82.2%) produced… CONTINUE READING

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