Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis.

@article{Vandenbroeck1997OccurrenceAC,
  title={Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis.},
  author={Koen Vandenbroeck and Gianvito Martino and M G Marrosu and Antonella Consiglio and Mauro Zaffaroni and Simona Vaccargiu and Diego Franciotta and Maria Ruggeri and Giancarlo Comi and Luigi Grimaldi},
  journal={Journal of neuroimmunology},
  year={1997},
  volume={76 1-2},
  pages={189-92}
}
An epistatic gene interaction has been advocated to explain disease susceptibility in multiple sclerosis (MS). Cytokine genes are possible candidates due to the central role played by cytokines in the regulation of the immune-mediated pathogenetic process leading to central nervous system demyelination in these patients. Since interleukin (IL)-4 gene polymorphisms have been associated with immune-mediated diseases, we have analysed the relationship between a variable number of tandem repeat… CONTINUE READING

From This Paper

Topics from this paper.
28 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…