Occurrence and behavior of the chiral anti‐inflammatory drug naproxen in an aquatic environment

@article{Suzuki2014OccurrenceAB,
  title={Occurrence and behavior of the chiral anti‐inflammatory drug naproxen in an aquatic environment},
  author={Toshinari Suzuki and Yukihiro Kosugi and Mitsugu Hosaka and Tetsuji Nishimura and Dai Nakae},
  journal={Environmental Toxicology and Chemistry},
  year={2014},
  volume={33}
}
The present study reports on the occurrence and chiral behavior of the anti‐inflammatory drug (S)‐naproxen (NAP)—(S)‐2‐(6‐methoxynaphthalen‐2‐yl)propionic acid—in an aquatic environment under both field and laboratory conditions. In influents and effluents of sewage treatment plants (STPs) in the Tama River basin (Tokyo), (S)‐NAP was detected at concentrations of 0.03 µg L−1 to 0.43 µg L−1 and 0.01 µg L−1 to 0.11 µg L−1, respectively. The concentrations of a major metabolite, 6‐O‐desmethyl NAP… 

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References

SHOWING 1-10 OF 48 REFERENCES

Occurrence and fate of anti-inflammatory drugs in wastewater treatment plants in Japan.

The fates of anti-inflammatory drugs (e.g., ibuprofen, naproxen, mefenamic acid and ketoprofen), which are frequently detected in the discharges of wastewater treatment plants (WWTPs) and river water

Occurrence and Environmental Behavior of the Chiral Pharmaceutical Drug Ibuprofen in Surface Waters and in Wastewater

Pharmaceutical compounds can reach detectable concentrations in rivers and lakes if production and use are sufficiently large and the compounds show some mobility and persistence in the aquatic

Photochemical degradation of naproxen in the aquatic environment.

The first-order rate constants of naproxen degradation were determined and the maximal value of rate constant was observed by UV/H2O2 process in water samples at pH = 6 (k = 0.997 min(-1)).

Photodegradation of common environmental pharmaceuticals and estrogens in river water

Photodegradation rates of five pharmaceuticals and of four estrogens and of five estrogens, which are common contaminants in the aquatic environment, were measured in both purified and river water at environmentally relevant concentrations (1–2 μg/L) and different oxygen concentrations.

Stability and Removal of Naproxen and Its Metabolite by Advanced Membrane Wastewater Treatment Plant and Micelle–Clay Complex

Naproxen, a non-steroidal anti-inflammatory drug, commonly used for fever, inflammation and for different health problems, as found for many pharmaceuticals has been recently detected in sewage

Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant.

Occurrence of pharmaceuticals in river water and their elimination in a pilot-scale drinking water treatment plant.

The treatment train was found to very effectively eliminate the pharmaceuticals from the rawwater using ferric salt coagulation, rapid sand filtration, ozonation, two-stage granular activated carbon filTration (GAC), and UV disinfection.

Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters.

The relative importance in terms of loads was carbamazepine, followed by diclofenac, naproxen, ibuprofen, clofibric acid, and ketoprofen; an overall removal rate was estimated in surface waters, under real-world conditions (in a lake), using field measurements and modeling.

Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.