Occurrence, efficacy, metabolism, and toxicity of triclosan.

  title={Occurrence, efficacy, metabolism, and toxicity of triclosan.},
  author={Jia-Long Fang and Robin L. Stingley and Frederick A Beland and Wafa A Harrouk and Debbie L Lumpkins and Paul Howard},
  journal={Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews},
  volume={28 3},
Triclosan has broad-spectrum anti-microbial activity against most gram-negative and gram-positive bacteria. It is widely used in personal care products, household items, medical devices, and clinical settings. Due to its extensive use, there is potential for humans in all age groups to receive life-time exposures to triclosan, and, indeed, triclosan has been detected in human tissues and the environment. Data gaps exist regarding the chronic dermal toxicity and carcinogenicity of triclosan… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 115 references

Pharmacokinetics of triclosan following oral ingestion in humans.

Journal of toxicology and environmental health. Part A • 2006
View 9 Excerpts
Highly Influenced

Percutaneous penetration and dermal metabolism of triclosan (2,4, 4'-trichloro-2'-hydroxydiphenyl ether).

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2000
View 7 Excerpts
Highly Influenced

Triclosan: a safety profile.

American journal of dentistry • 1989
View 10 Excerpts
Highly Influenced

Toxicology of 2, 4, 4'-trichloro-2'-hydroxy-diphenyl ether.

IMS, Industrial medicine and surgery • 1969
View 10 Excerpts
Highly Influenced

Identification of hydroxylated PCB metabolites and other phenolic halogenated pollutants in human blood plasma.

Archives of environmental contamination and toxicology • 2002
View 2 Excerpts
Highly Influenced

Buccal absorption of triclosan following topical mouthrinse application.

American journal of dentistry • 2000
View 5 Excerpts
Highly Influenced

Triclosan: applications and safety.

American journal of infection control • 1996
View 6 Excerpts
Highly Influenced

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